Searchable abstracts of presentations at key conferences on calcified tissues

ba0004p118 | (1) | ICCBH2015

Changes in total body and regional bone mass in relation to body composition in children with osteogenesis imperfecta treated with pamidronate

Sritharan Shironisha , Gopal-Kothandapani Jaya Sujatha , Bishop Nick , Dimitri Paul

Background: In patients with osteogenesis imperfecta (OI), a rise in age-specific total body and regional bone mass is well recognised. In contrast changes in body size-adjusted bone mass in relation to changes in body composition following pamidronate therapy remain relatively unexplored.Methods: Changes in total and regional bone mass in relation to body composition in children with OI receiving pamidronate (3 mg/kg per day over 3 days, 3 monthly) were...

ba0005p97 | Calciotropic and phosphotropic hormones and mineral metabolism | ECTS2016

Vitamin D therapy: the effects of race, skin colour and genotype

Sujatha Jaya , Kothandapani Gopal , Evans Lucy , Fatma Gossiel , Walsh Jennifer , Eastell Richard , Bishop Nick

Background: It is well established that Asians have lower levels of vitamin D (25OHD) when compared to Caucasians. Vitamin D binding protein (DBP) levels are also lower in some races than in Caucasians.Objectives: i) To find out whether DBP is lower in Asians; ii) To find out whether free 25OHD is lower in Asians; iii) To find out whether PTH is increased in Asians and interpret this in relation to 25OHD levels and iv) To find out whether the increment i...